Review by: Robert Wu, 2020 Introduction Osteoarthritis of the knee is the most common cause of disability in the lower limb in adults over 50 years old, impacting the lives of more than 30 million Americans alone. In more severe cases, patients may experience persistent pain that disrupts sleep or Read more…
Review by: Rei Mitsuyama, Brown University, 2020 Introduction Hematologic malignancies are a heterogeneous group of cancers for which cytotoxic chemotherapy is the mainstay of treatment. Patients often require ports (implantable venous access systems) to maintain reliable venous access for drug administration. Despite advances in antimicrobial therapy and dedication to Read more…
Monica Matsumoto, MS4, University of Chicago Pritzker School of Medicine Pulmonary embolism (PE) is the leading cause of death from venous thromboembolic (VTE) disease and is an important, preventable source of morbidity and mortality globally1. The incidence of PE has been rising with substantial treatment-associated costs, with the estimated cost Read more…
Rei Mitsuyama, MS2, MD Student, Brown University Summary: Spontaneous iliopsoas and rectus sheath hematomas arising in patients on anticoagulant therapy are more likely to require embolic treatment rather than conservative management. Of the numerous embolic agents available, Glubran 2 NBCA-MS glue seems to be an efficacious option that causes Read more…
Author: Rei Mitsuyama, MS3, Brown University Introduction Benign superior vena cava (SVC) syndrome is caused by nonmalignant obstruction of the SVC. The most common causes are long-term central lines, long-term cardiac devices, and fibrosing mediastinitis. Symptoms may include headache, facial swelling, and upper limb edema which may present acutely or Read more…
Author: Rayan Abboud, MS, Medical Student, Wake Forest School of Medicine Editor: Justin Foster, MD, PGY-4 Rochester Regional Health, Rochester, NY Introduction In patients in need of intermediate or long-term hemodialysis, tunneled hemodialysis catheters [1] are initially used until arteriovenous access (e.g. fistula) can be established. Like other central venous Read more…
Mahati Mokkarala, Washington University School of Medicine, 2019 Editor: Justin Foster, MD, PGY-4 Rochester Regional Health, Rochester, NY Introduction: Multiple studies have shown that breast cancer genomic profile can affect metastatic breast cancer treatment effectiveness. Breast cancer gene mutations have been linked towards increased radiation therapy resistance. This JVIR Read more…
Yang (John) Qiao, Texas A&M University College of Medicine, 2019 Editor: Justin Foster, MD, PGY-4 Rochester Regional Health, Rochester, NY Renal cell carcinoma (RCC) is an oncologic disease originating from the cells lining the small tubes of the kidney, the functional filtration organs of the body. Symptoms of RCC can Read more…
By: Paul Ippolito, Rutgers New Jersey Medical School, 2020 Edited by: Giovanni Santoro, DO Pulmonary embolism refers to an acute blockage or obstruction of a pulmonary artery by a thrombus formed at another anatomical site, commonly the deep veins of the legs, that has traveled to the lungs [1]. Inferior Read more…
PURPOSE To evaluate the safety and efficacy of combination therapy (TACE+ sorafenib) in patients with advanced stage HCC. STUDY DESIGN Open-label, non-randomized, single-arm multicenter phase II clinical trial. The primary endpoint was defined as the rate of completion of the treatment protocol (i.e., 2 months duration of sorafenib following TACE); Read more…